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Ondansetron-hydrochloride Drug Info

Generic name: Ondansetron hydrochloride
Brand names: Zofran ODT, Zofran

Why is Ondansetron hydrochloride prescribed?

Zofran is used for the prevention of nausea and vomiting caused by radiation therapy and chemotherapy for cancer, and, in some cases, to prevent these problems following surgery.
Most important fact about Ondansetron hydrochloride

To ensure the maximum effect, it is important to take all doses of Zofran exactly as prescribed by your doctor.

How should you take Ondansetron hydrochloride?

Your doctor will tell you how much drug to take and how often, depending on the type of therapy you will be having.

Zofran is available in three forms: an oral solution, tablets that you swallow with water, and orally disintegrating tablets that can be swallowed with saliva alone (Zofran ODT). If you're taking the orally disintegrating tablets, don't remove them from the blister pack until it's time for a dose. Then peel off the foil backing with dry hands, gently remove the tablet, and immediately place it on your tongue. Do not attempt to push the tablets through the foil.

--If you miss a dose...
Take the forgotten dose as soon as you remember.
--Storage instructions...

Store Zofran at room temperature. Protect from light. Keep the drug in the carton it came in. Store oral solution bottles upright.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Zofran.

  • More common side effects may include:
    Constipation, diarrhea, dizziness, fatigue, headache
  • When Zofran is used to prevent nausea and vomiting after surgery, the following side effects may occur:
    Anxiety, difficulty breathing, difficulty urinating, dizziness, drowsiness, female reproductive disorders, fever, headache, itching, low blood pressure, shivers, slow heartbeat

    • Why should Ondansetron hydrochloride not be prescribed?

    If you are sensitive to or have ever had an allergic reaction to ondansetron hydrochloride, you should not take Ondansetron hydrochloride. Make sure that your doctor is aware of any drug reactions that you have experienced.
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